An educational hub for advancing the use of Ozonated Glycerin (OG) based upon research and clinical experience.
Built by practitioners, for practitioners.
Why It Matters
OG extends the power of ozone therapy into a safe, portable, and stable medium for humans and animals.
Dr. Jim Bridge, DVM, CVA, FAAO, has applied OG in over 400 clinical cases — from chronic wounds to cancer, periodontal infections, and pain syndromes — with consistent results in healing and pain reduction.
“OG relieves pain, reduces inflammation, and accelerates tissue regeneration — without gas, odor, or residue.” — Dr. Bridge (AAOT 2018)
The Breakthrough
is a single-ingredient compound — pure organic glycerin infused with medical-grade ozone— developed by Charles Marchand in 1885 and rediscovered again in the past decade. OG is water- and oil-soluble, shelf-stable for 90 days, and backed by over 100 published papers demonstrating:
Antibacterial, antiviral, antifungal, and antiparasitic activity
Anti-inflammatory, antioxidant, and wound-healing properties
Pain relief and immune modulation in clinical and veterinary use
First discovered by Dr. Gotaro Shiota and validated by Japanese and Italian research teams, OG represents a bridge between ozone therapy and regenerative medicine.
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PurO3® Ozonated Glycerin — The trusted source for clinical and cosmetic OG applications
OG PRO Courses — Structured learning for healthcare practitioners, dentists, veterinarians, and health minded individuals
COMING SOON
Research Library — international publications indexed by topic
Clinical Community — Discussion board and case repository
“Think of Ozonated Glycerin as long-acting ozone. We have to have standards for its use.”
“Ozonated glycerin is a monumental breakthrough and beyond a game changer. I believe, when this is brought forth to the world that those who brought it forward will be deserving of a Nobel Prize.”
“The introduction of ozonated glycerin in dentistry, especially the biologic game, is a paradigm shift, it makes a significant difference in every aspect of dentistry.”
“The use of Ozonated Glycerin in dental practice is just a game changer.”
“OG Pro is providing the leadership our ozone community needs—bringing science, clinical experience, and practitioner collaboration together under one umbrella to take this field to the next level.”
Join the Movement
A collaborative network uniting physicians, dentists, veterinarians, and researchers using OG in practice.
Members receive:
OG PRO Notes Handbook – Clinical Breakthroughs in Ozonated Glycerin
Exclusive Access to Courses on mechanisms, applications & protocols
Founders Discounts and early access to tools and supplies
Online Community Membership for case discussion and Q&A
Sample Notes & Treatment Templates for clinical integration
Learn. Apply. Grow.
Collaborate with practitioners expanding OG into mainstream medicine.
From Dr. Charles Marchand’s 19th-century foundation of ozonated therapies to Dr. Jim Bridge’s North American clinical adaptation, OG PRO stands for evidence-based innovation in oxygen medicine.
“A new oxygen compound for a new era of healing — safe for humans, animals, and the planet.”
To establish OG as a trusted, evidence-based tool—uniting physicians, dentists, veterinarians, and health innovators to pioneer oxygen-based healing worldwide.
Our Story
Founded by Pamela Holloway, RN, MS and Dr. Jim Bridge, DVM, CVA, FAAO, OG Pro was born from a shared conviction that modern health must rediscover the regenerative power of oxygen. From the discovery made by Charles Marchand in the late 1800’s to Dr. Bridge’s years of veterinary research and Pamela’s leadership in integrative health, OG Pro exists to carry this science forward to practitioners who are looking for simple modalities that restore health.
Join Us
Become part of a growing global network of professionals and educators shaping the future of oxygen-based therapeutics. Your membership fuels collaboration, innovation, and healing that transcends boundaries. Become a member of OGPro.org—where science meets practice, and oxygen meets purpose.
OGpro Notes
Bridging Science into Practice
Ozonated glycerin (OG) represents one of the most profound biochemical discoveries in oxidative medicine since hydrogen peroxide therapy. Born from the pioneering chemistry of Dr. Charles Marchand (1899) and advanced by Japanese researchers combined with clinical application and research by Dr. James Bridge, DVM, this stabilized ozone compound has been shown to possess broad-spectrum antimicrobial, anti-inflammatory, regenerative, and analgesic effects—without the instability of ozone gas or ozonated water.
Available November 6, 2025 | Sign-up to be notified
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